发明申请
US20110052576A1 VEGF-SPECIFIC ANTAGONISTS FOR ADJUVANT AND NEOADJUVANT THERAPY AND THE TREATMENT OF EARLY STAGE TUMORS
审中-公开
VEGF特异性拮抗剂用于治疗和治疗早期治疗和早期阶段肿瘤
- 专利标题: VEGF-SPECIFIC ANTAGONISTS FOR ADJUVANT AND NEOADJUVANT THERAPY AND THE TREATMENT OF EARLY STAGE TUMORS
- 专利标题(中): VEGF特异性拮抗剂用于治疗和治疗早期治疗和早期阶段肿瘤
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申请号: US12826001申请日: 2010-06-29
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公开(公告)号: US20110052576A1公开(公告)日: 2011-03-03
- 发明人: NAPOLEONE FERRARA , NINA KORSISAARI , ROBERT D. MASS
- 申请人: NAPOLEONE FERRARA , NINA KORSISAARI , ROBERT D. MASS
- 申请人地址: US CA SOUTH SAN FRANCISCO
- 专利权人: GENENTECH, INC.
- 当前专利权人: GENENTECH, INC.
- 当前专利权人地址: US CA SOUTH SAN FRANCISCO
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; A61K31/7088 ; A61K31/713 ; A61K39/00 ; A61P35/00
摘要:
Disclosed herein are methods of treating benign, pre-cancerous, or non-metastatic tumors using an anti-VEGF-specific antagonist. Also disclosed are methods of treating a subject at risk of developing benign, pre-cancerous, or non-metastatic tumors using an anti-VEGF-specific antagonist. Also disclosed are methods of treating or preventing recurrence of a tumor using an anti-VEGF-specific antagonist as well as use of VEGF-specific antagonists in neoadjuvant and adjuvant cancer therapy.
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