发明申请
- 专利标题： PAKs as Modifiers of the CHK Pathway and Methods of Use
- 专利标题（中）： PAK作为CHK途径和使用方法的修饰物
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申请号： US12828515申请日： 2010-07-01
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公开(公告)号： US20110059066A1公开(公告)日： 2011-03-10
- 发明人: Helen Francis-Lang , Siobhan Roche , Lickteig Kim
- 申请人： Helen Francis-Lang , Siobhan Roche , Lickteig Kim
- 申请人地址： US CA South San Francisco
- 专利权人： EXELIXIS, INC.
- 当前专利权人： EXELIXIS, INC.
- 当前专利权人地址： US CA South San Francisco
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61P35/00 ; C12N5/02 ; C12Q1/48 ; C12Q1/68 ; G01N33/573
摘要：
Human PAK genes are identified as modulators of the CHK pathway, and thus are therapeutic targets for disorders associated with defective CHK function. Methods for identifying modulators of CHK, comprising screening for agents that modulate the activity of PAK are provided.
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