发明申请
- 专利标题： C/CLP Antagonists And Methods Of Use Thereof
- 专利标题（中）： C / CLP拮抗剂及其使用方法
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申请号： US12351145申请日： 2009-01-09
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公开(公告)号： US20110059100A1公开(公告)日： 2011-03-10
- 发明人: Jennifer L. Reed , Wendy I. White , Anthony Coyle , Alexander Kozhich , Jack Elias , Nanci Donacki , Changshou Gao , Herren Wu
- 申请人： Jennifer L. Reed , Wendy I. White , Anthony Coyle , Alexander Kozhich , Jack Elias , Nanci Donacki , Changshou Gao , Herren Wu
- 申请人地址： US MD Gaithersburg US CT New Haven
- 专利权人： MEDIMMUNE, LLC,YALE UNIVERSITY
- 当前专利权人： MEDIMMUNE, LLC,YALE UNIVERSITY
- 当前专利权人地址： US MD Gaithersburg US CT New Haven
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/00 ; A61P11/00
摘要：
The invention relates to the novel discovery that antagonizing a C/CLP can be useful for the treatment of diseases associated with the upregulation of one or more C/CLP such as Th2-driven and/or IL-13 mediated inflammatory diseases. Accordingly the present invention provides C/CLP antagonists and also provides compositions and methods for the prevention, management, treatment or amelioration of an inflammatory condition associated with the upregulation of a C/CLP or one or more symptoms thereof and/or the inhibition of IL-13 mediated inflammation.