发明申请
- 专利标题: REAGENTS AND METHODS FOR DETECTING INFLUENZA VIRUS PROTEINS
- 专利标题(中): 用于检测流感病毒蛋白的试剂和方法
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申请号: US12920838申请日: 2009-03-10
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公开(公告)号: US20110059472A1公开(公告)日: 2011-03-10
- 发明人: Xuguang (Sean) Li , Runtao He , Gary Van Domselaar
- 申请人: Xuguang (Sean) Li , Runtao He , Gary Van Domselaar
- 国际申请: PCT/CA09/00283 WO 20090310
- 主分类号: G01N33/53
- IPC分类号: G01N33/53 ; C07K16/08 ; C07K7/08
摘要:
Antibodies that specifically bind to a peptide having an amino acid sequence as found at the N-terminus of the HA2 fusion peptide of the influenza A virus may be raised by inoculating a mammal with a conjugate of the peptide. In one embodiment, the conjugate comprises the peptide linked to a spacer (e.g. 6-aminocaproic acid) and a carrier protein (e.g. KLH). The antibodies may be used as a universal reagent for detecting HA proteins of influenza viruses. The antibodies are useful as versatile reagents for laboratory research and vaccine potency determination, especially in the event of pandemic influenza outbreaks.
公开/授权文献
- US08669046B2 Reagents and methods for detecting influenza virus proteins 公开/授权日:2014-03-11