发明申请
US20110060017A1 NOVEL 1,2,3-TRIAZOLE DERIVATIVES USEFUL AS MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS
审中-公开
新的1,2,3-三唑衍生物有用作为非线性乙酰胆碱受体的调节剂
- 专利标题： NOVEL 1,2,3-TRIAZOLE DERIVATIVES USEFUL AS MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS
- 专利标题（中）： 新的1,2,3-三唑衍生物有用作为非线性乙酰胆碱受体的调节剂
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申请号： US12921995申请日： 2009-03-09
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公开(公告)号： US20110060017A1公开(公告)日： 2011-03-10
- 发明人: Antonio Nardi , Jeppe Kejser Christensen , Dan Peters
- 申请人： Antonio Nardi , Jeppe Kejser Christensen , Dan Peters
- 申请人地址： DK Ballerup
- 专利权人： Neurosearch A/S
- 当前专利权人： Neurosearch A/S
- 当前专利权人地址： DK Ballerup
- 优先权： DKPA200800370 20080311; DKPA200801078 20080807
- 国际申请： PCT/EP2009/052729 WO 20090309
- 主分类号： A61K31/4192
- IPC分类号： A61K31/4192 ; C07D249/04 ; A61P25/00 ; A61P25/20 ; A61P25/16 ; A61P25/28 ; A61P25/24 ; A61P25/18 ; A61P21/00 ; A61P25/30 ; A61P29/00 ; A61P15/00 ; A61P3/10 ; A61P1/00
摘要：
This invention relates to novel 1,2,3-triazole derivatives, which are found to be modulators of the nicotinic acetyl-choline receptors. Due to their pharmacological profile, the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
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