发明申请
US20110065634A1 GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE
有权
GLUCAGON受体拮抗剂,组合物及其使用方法
- 专利标题: GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE
- 专利标题(中): GLUCAGON受体拮抗剂,组合物及其使用方法
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申请号: US12992771申请日: 2009-05-13
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公开(公告)号: US20110065634A1公开(公告)日: 2011-03-17
- 发明人: William J. Greenlee , Andrew Stamford , Michael W. Miller , Duane Eugene DeMong
- 申请人: William J. Greenlee , Andrew Stamford , Michael W. Miller , Duane Eugene DeMong
- 国际申请: PCT/US09/43722 WO 20090513
- 主分类号: A61K38/28
- IPC分类号: A61K38/28 ; C07D231/18 ; A61K31/415 ; C07D231/22 ; C07D231/38 ; C07D401/12 ; A61K31/41 ; C07D231/12 ; A61K38/22 ; A61K31/7004 ; A61P3/00
摘要:
The present invention relates to compounds of general formula (I), wherein ring A, ring B, R1, R2, R3, Z, and L1 are selected independently of each other and are as defined herein, to compositions comprising the compounds, and methods of using the compounds as glucagon receptor antagonists and for the treatment or prevention of type 2 diabetes and conditions related thereto.
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