Invention Application
- Patent Title: PHENYLPYRAZOLE DERIVATIVES
- Patent Title (中): 苯并噻唑衍生物
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Application No.: US12951978Application Date: 2010-11-22
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Publication No.: US20110065668A1Publication Date: 2011-03-17
- Inventor: Toshio NAKAMURA , Makoto Tatsuzuki , Dai Nozawa , Tomoko Tamita , Seiji Masuda , Hiroshi Ohta , Shuhei Kashiwa , Aya Fujino , Shigeyuki Chaki , Toshiharu Shimazaki
- Applicant: Toshio NAKAMURA , Makoto Tatsuzuki , Dai Nozawa , Tomoko Tamita , Seiji Masuda , Hiroshi Ohta , Shuhei Kashiwa , Aya Fujino , Shigeyuki Chaki , Toshiharu Shimazaki
- Applicant Address: JP Tokyo
- Assignee: TAISHO PHARMACEUTICAL CO., LTD.
- Current Assignee: TAISHO PHARMACEUTICAL CO., LTD.
- Current Assignee Address: JP Tokyo
- Priority: JP2007294040 20071113; JP2008153736 20080612
- Main IPC: A61K31/695
- IPC: A61K31/695 ; A61K31/415 ; A61K31/5377 ; A61K31/553 ; A61P25/28 ; A61P25/18 ; A61P3/10 ; A61P25/24 ; A61P25/08 ; A61P25/00

Abstract:
The present invention provides a prophylactic or therapeutic agent for dementia, Alzheimer's disease, attention-deficit hyperactivity disorder, schizophrenia, eating disorders, obesity, diabetes, hyperlipidemia, sleep disorders, narcolepsy, sleep apnea syndrome, circadian rhythm disorder, depression, allergic rhinitis or other diseases.A phenylpyrazole derivative represented by formula (1) or a pharmaceutically acceptable salt thereof: {wherein R1 and R2, which may be the same or different, each represent C1-C6 alkyl or C3-C8 cycloalkyl, or R1 and R2 are attached to each other together with their adjacent nitrogen atom to form a 4- to 7-membered saturated heterocyclic ring (wherein said saturated heterocyclic ring may be substituted with halogen or C1-C6 alkyl), n represents an integer of 0 to 2, T represents a hydrogen atom, halogen or C1-C6 alkyl, and R represents formula (I): or the like}.
Public/Granted literature
- US08193176B2 Phenylpyrazole derivatives Public/Granted day:2012-06-05
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