发明申请
- 专利标题： HYDRAZIDE COMPOUNDS AND USES THEREOF
- 专利标题（中）： 氢化物化合物及其用途
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申请号： US12596240申请日： 2008-04-17
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公开(公告)号： US20110065687A1公开(公告)日： 2011-03-17
- 发明人: Michael Schwaebe , Johnny Yasuo Nagasawa , Mustapha Haddach
- 申请人： Michael Schwaebe , Johnny Yasuo Nagasawa , Mustapha Haddach
- 国际申请： PCT/US08/60677 WO 20080417
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D513/14 ; A61K31/497 ; A61K31/496 ; A61K31/551 ; C07D498/04 ; C07D471/04 ; C07D513/04 ; C07D498/14 ; A61K31/5383 ; A61K31/4985 ; A61K31/542 ; A61P35/00 ; A61P31/12 ; A61P31/04 ; A61P31/10
摘要：
This application relates to certain novel polycyclic compounds that interact with quadruplex-forming regions of polynucleotides and thereby inhibit translation of genetic information into polypeptides. These compounds can thus provide anticancer and antibacterial and antiviral effects. The invention includes novel compounds and pharmaceutical compositions, and methods of using them to treat cancer and other conditions.
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