- 专利标题: METHODS OF USE OF ANTIVIRAL COMPOUNDS
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申请号: US12881038申请日: 2010-09-13
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公开(公告)号: US20110065766A1公开(公告)日: 2011-03-17
- 发明人: Jizhou Wang , Xiaodong Fan , Lidia Cristian
- 申请人: Jizhou Wang , Xiaodong Fan , Lidia Cristian
- 主分类号: A61K31/4196
- IPC分类号: A61K31/4196 ; A61K31/13 ; A61K31/133 ; A61K31/357 ; A61K31/155 ; A61K31/4164 ; A61K31/415 ; C07C211/19 ; C07C251/20 ; C07D317/72 ; C07C279/16 ; C07D249/08 ; C07D249/14 ; C07D231/38 ; C07D233/10 ; C07D233/58 ; A61P31/16
摘要:
The present invention relates, in part, to methods of treatment, prevention, and inhibition of viral disorders. In one aspect, the present invention relates to inhibition of the M2 proton channel of influenza viruses (e.g. influenza A virus) and other similar viroporins (e.g., VP24 of Ebola and Marburg viruses; and NS3 protein of Bluetongue). The present invention further relates, inter alia, to compounds which have been shown to possess antiviral activity, in particular, inhibiting the M2 proton channel of influenza viruses.
公开/授权文献
- US08440720B2 Methods of use of antiviral compounds 公开/授权日:2013-05-14