An internal combustion engine has an air intake system with an air intake pipe and which communicates with a combustion chamber of a cylinder as a function of a switch position of a gas inlet valve. Furthermore, a compressor is disposed in the air intake system and is embodied for the purpose of compressing a mass air flow. Also, a throttle valve is disposed in the air intake system downstream of the compressor and by which the compressed mass air flow into the air intake pipe can be throttled. The internal combustion engine furthermore has a differential pressure sensor which is disposed in the air intake system and is embodied for the purpose of measuring a differential pressure between a charge pressure that prevails downstream of the compressor and upstream of the throttle valve and an ambient pressure that prevails outside of the air intake system.