发明申请
US20110071160A1 1,3-DIHYDRO-2H-PYRROLO[3,2-b]PYRIDIN-2-ONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF
有权
1,3-二氢-2H-吡喃并[3,2-b]吡啶-2-酮衍生物，其制备方法及其治疗用途
![1,3-DIHYDRO-2H-PYRROLO[3,2-b]PYRIDIN-2-ONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF](/docs/US/2011-03-24/US20110071160A1/abs.jpg.600x600.jpg)
- 专利标题： 1,3-DIHYDRO-2H-PYRROLO[3,2-b]PYRIDIN-2-ONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF
- 专利标题（中）： 1,3-二氢-2H-吡喃并[3,2-b]吡啶-2-酮衍生物，其制备方法及其治疗用途
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申请号： US12905287申请日： 2010-10-15
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公开(公告)号： US20110071160A1公开(公告)日： 2011-03-24
- 发明人: Cedric COUTURIER , Loic FOULON , Claudine SERRADEIL-LE GAL , Gerard VALETTE
- 申请人： Cedric COUTURIER , Loic FOULON , Claudine SERRADEIL-LE GAL , Gerard VALETTE
- 申请人地址： FR Paris
- 专利权人： SANOFI-AVENTIS
- 当前专利权人： SANOFI-AVENTIS
- 当前专利权人地址： FR Paris
- 优先权： FR0802195 20080421
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; C07D471/04 ; A61K31/437 ; A61P15/06 ; A61P15/00 ; A61P15/08 ; A61P13/06 ; A61P9/12 ; A61P25/00 ; A61P3/10
![1,3-DIHYDRO-2H-PYRROLO[3,2-b]PYRIDIN-2-ONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF](/abs-image/US/2011/03/24/US20110071160A1/abs.jpg.150x150.jpg)
摘要：
The subject matter of the present invention are compounds corresponding to formula (I): in which: X is an unsubstituted or substituted divalent (C1-C5)alkylene radical; R1 is an —NR8R9 group; or an unsubstituted or substituted piperidin-3-yl or piperidin-4-yl radical; R2 is a hydrogen atom, a halogen atom, an Alk group or an OAlk group; R3 is a hydrogen atom, a halogen atom, an Alk group or an OAlk group; R4 is a hydrogen atom, a halogen atom, an Alk group, a hydroxyl or an OAlk group; and R5 is a hydrogen atom, a halogen atom, an Alk group, a hydroxyl or an OAlk group.
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