发明申请
- 专利标题： INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY
- 专利标题（中）： 蛋白酪氨酸激酶活性的抑制剂
-
申请号： US12964289申请日： 2010-12-09
-
公开(公告)号： US20110077240A1公开(公告)日： 2011-03-31
- 发明人: Michael Mannion , Stéphane Raeppel , Stephen William Claridge , Frédéric Gaudette , Lijie Zhan , Ljubomir Isakovic , Oscar Mario Saavedra , Tetsuyuki Uno , Masashi Kishida , Arkadii Vaisburg
- 申请人： Michael Mannion , Stéphane Raeppel , Stephen William Claridge , Frédéric Gaudette , Lijie Zhan , Ljubomir Isakovic , Oscar Mario Saavedra , Tetsuyuki Uno , Masashi Kishida , Arkadii Vaisburg
- 主分类号： A61K31/541
- IPC分类号： A61K31/541 ; C07D495/04 ; A61K31/4365 ; A61P27/02
摘要：
This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling. The invention also provides compounds, compositions and methods for treating cell proliferative diseases and conditions and opthalmological diseases, disorders and conditions.
公开/授权文献
- US08759522B2 Inhibitors of protein tyrosine kinase activity 公开/授权日：2014-06-24
信息查询
