发明申请
US20110081678A1 METHOD FOR PRODUCING BETA-ALANYL-AMINO ACID OR DERIVATIVE THEREOF
审中-公开
生产β-氨基酸或其衍生物的方法
- 专利标题: METHOD FOR PRODUCING BETA-ALANYL-AMINO ACID OR DERIVATIVE THEREOF
- 专利标题(中): 生产β-氨基酸或其衍生物的方法
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申请号: US12943509申请日: 2010-11-10
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公开(公告)号: US20110081678A1公开(公告)日: 2011-04-07
- 发明人: Rie Takeshita , Yasuaki Takakura , Shunichi Suzuki , Kenzo Yokozeki
- 申请人: Rie Takeshita , Yasuaki Takakura , Shunichi Suzuki , Kenzo Yokozeki
- 优先权: JP2008-125123 20080512
- 主分类号: C12P21/02
- IPC分类号: C12P21/02 ; C07H21/04 ; C12N9/00 ; C12N5/10
摘要:
The present invention provides a method for efficiently producing a β-alanyl-amino acid (e.g., carnosine) or derivative thereof. Specifically, it provides a method for producing a β-alanyl-amino acid (e.g., β-alanyl-histidine) or derivative thereof, by reacting a β-alanyl ester or a β-alanyl amide and an amino acid or derivative thereof in the presence of an enzyme or an enzyme-containing product that has an ability to form the β-alanyl-amino acid (e.g., β-alanyl-histidine) or derivative thereof from the β-alanyl ester or the β-alanyl amide and the amino acid (e.g., histidine) or derivative thereof. The present invention also provides a protein which is able to catalyze production of a β-alanyl-amino acid or derivative thereof from a β-alanyl ester or a β-alanyl amide and an amino acid or derivative thereof, and a polynucleotide encoding said protein.