发明申请
- 专利标题： RADIOSENSITIZATION OF TUMORS WITH INDAZOLPYRROLOTRIAZINES FOR RADIOTHERAPY
- 专利标题（中）： 肿瘤放射治疗与放射治疗的吲哚酚
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申请号： US12937241申请日： 2009-04-10
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公开(公告)号： US20110086850A1公开(公告)日： 2011-04-14
- 发明人: Kie-Kian Ang , Luka Milas
- 申请人： Kie-Kian Ang , Luka Milas
- 申请人地址： US TX Austin
- 专利权人： Board of Regents, The University of Texas System
- 当前专利权人： Board of Regents, The University of Texas System
- 当前专利权人地址： US TX Austin
- 国际申请： PCT/US09/02255 WO 20090410
- 主分类号： A61K31/5355
- IPC分类号： A61K31/5355 ; C12N5/071 ; A61K31/53 ; A61P35/00
摘要：
Provided herein is a method of radiosensitizing a tumor in a subject, which comprises administering to the subject a radiosensitizing amount of an indazolpyrrolotriazine of Formula I. Also provided herein is a method of treating a tumor in a subject, which comprises the steps of administering to the subject a radiosensitizing amount of an indazolpyrrolotriazine of Formula I, and a therapeutically effective fraction of radiation.
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