- 专利标题: 3-CINNOLINECARBOXAMIDE DERIVATIVES AND THEIR USE FOR TREATING CANCER
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申请号: US12781277申请日: 2010-05-17
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公开(公告)号: US20110098283A1公开(公告)日: 2011-04-28
- 发明人: Leslie Dakin , Claude Afona Ogoe , David Scott , XiaoLan Zheng
- 申请人: Leslie Dakin , Claude Afona Ogoe , David Scott , XiaoLan Zheng
- 专利权人: ASTRAZENECA AB
- 当前专利权人: ASTRAZENECA AB
- 主分类号: A61K31/502
- IPC分类号: A61K31/502 ; C07D237/28 ; C07D401/10 ; C07D403/10 ; C07D413/10 ; A61K31/55 ; A61K31/5377 ; A61P35/00 ; C12N9/99
摘要:
The invention relates to chemical compounds of formula (I): or pharmaceutically acceptable salts thereof which possess CSF-1R kinase inhibitory activity and are accordingly useful for their anti-cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm-blooded animal such as man.