发明申请
- 专利标题： BIOMARKERS FOR AMYOTROPHIC LATERAL SCLEROSIS
- 专利标题（中）： 生物标志物对于前列腺切除术
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申请号： US12957686申请日： 2010-12-01
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公开(公告)号： US20110104739A1公开(公告)日： 2011-05-05
- 发明人: Robert P. Bowser , Srikanth Ranganathan
- 申请人： Robert P. Bowser , Srikanth Ranganathan
- 专利权人： University of Pittsburgh - Of the Commonwealth System of Higher Education
- 当前专利权人： University of Pittsburgh - Of the Commonwealth System of Higher Education
- 主分类号： C12Q1/02
- IPC分类号： C12Q1/02 ; H01J49/26
摘要：
The invention provides a method for diagnosing amyotrophic lateral sclerosis (ALS) in a subject, a method for assessing the effectiveness of a drug in treating ALS, and a method for determining the site of onset of ALS in a subject. Each method comprises (a) obtaining a sample from the subject, (b) analyzing the proteins in the sample by mass spectroscopy, and (c) determining a mass spectral profile for the sample. In some embodiments, the method comprises comparing the mass spectral profile of the sample to the mass spectral profile of a positive or a negative standard.
公开/授权文献
- US08202510B2 Biomarkers for amyotrophic lateral sclerosis 公开/授权日：2012-06-19
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