发明申请
US20110105485A1 Alpha-(N-Sulfonamido)Acetamide Derivatives as Beta-Amyloid Inhibitors
有权
α-（N-磺酰氨基）乙酰胺衍生物作为β-淀粉样蛋白抑制剂
- 专利标题： Alpha-(N-Sulfonamido)Acetamide Derivatives as Beta-Amyloid Inhibitors
- 专利标题（中）： α-（N-磺酰氨基）乙酰胺衍生物作为β-淀粉样蛋白抑制剂
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申请号： US12840612申请日： 2010-07-21
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公开(公告)号： US20110105485A1公开(公告)日： 2011-05-05
- 发明人: Michael F. Parker , Katharine E. McElhone , Robert A. Mate , Joanne J. Bronson , Yonghua Gai , Carl P. Bergstrom , Lawrence R. Marcin , John E. Macor
- 申请人： Michael F. Parker , Katharine E. McElhone , Robert A. Mate , Joanne J. Bronson , Yonghua Gai , Carl P. Bergstrom , Lawrence R. Marcin , John E. Macor
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 主分类号： A61K31/541
- IPC分类号： A61K31/541 ; A61K31/18 ; C07C311/46 ; A61K31/277 ; C07D233/61 ; A61K31/4164 ; C07D295/14 ; A61K31/5375 ; C07D211/34 ; A61K31/4453 ; A61K31/54 ; C07D217/04 ; A61K31/472 ; A61K31/216 ; A61K31/495 ; C07D211/16 ; C07D417/06 ; A61P25/28 ; A61P25/00
摘要：
There is provided a series of novel α-(N-sulfonamido)acetamide compounds of the Formula (I) wherein R, R1, R2 and R3 are defined herein, which are inhibitors of β-amyloid peptide (β-AP) production and are useful in the treatment of Alzheimer's Disease and other conditions affected by anti-amyloid activity.
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