发明申请
- 专利标题： KIFS as Modifiers of the RHO Pathway and Methods of Use
- 专利标题（中）： KIFS作为RHO途径和使用方法的修饰符
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申请号： US12890412申请日： 2010-09-24
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公开(公告)号： US20110111402A1公开(公告)日： 2011-05-12
- 发明人: Joanne ADAMKEWICZ , Craig D. AMUNDSEN , Lynn Margaret BJERKE , George Ross FRANCIS , Timothy S. HEUER , Kim LICKTEIG , Monique NICOLL
- 申请人： Joanne ADAMKEWICZ , Craig D. AMUNDSEN , Lynn Margaret BJERKE , George Ross FRANCIS , Timothy S. HEUER , Kim LICKTEIG , Monique NICOLL
- 申请人地址： US CA South San Francisco
- 专利权人： EXELIXIS INC.
- 当前专利权人： EXELIXIS INC.
- 当前专利权人地址： US CA South San Francisco
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; G01N33/566
摘要：
Human KIF23 genes are identified as modulators of the RHO pathway, and thus are therapeutic targets for disorders associated with defective RHO function. Methods for identifying modulators of RHO, comprising screening for agents that modulate the activity of KIF23 are provided.
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