专利检索 ap:("Joanne ADAMKEWICZ" OR "Craig D. AMUNDSEN" OR "Lynn Margaret BJERKE" OR "George Ross FRANCIS" OR "Timothy S. HEUER" OR "Kim LICKTEIG" OR "Monique NICOLL") AND inv:"Monique NICOLL" 第 1 页

1.

发明申请
KIFS as Modifiers of the RHO Pathway and Methods of Use 审中-公开
标题翻译： KIFS作为RHO途径和使用方法的修饰符

公开(公告)号：US20110111402A1

公开(公告)日：2011-05-12

申请号：US12890412

申请日：2010-09-24

申请人： Joanne ADAMKEWICZ , Craig D. AMUNDSEN , Lynn Margaret BJERKE , George Ross FRANCIS , Timothy S. HEUER , Kim LICKTEIG , Monique NICOLL

发明人： Joanne ADAMKEWICZ , Craig D. AMUNDSEN , Lynn Margaret BJERKE , George Ross FRANCIS , Timothy S. HEUER , Kim LICKTEIG , Monique NICOLL

IPC分类号： C12Q1/68 , G01N33/566

CPC分类号： G01N33/574 , G01N2333/4703 , G01N2500/00

摘要： Human KIF23 genes are identified as modulators of the RHO pathway, and thus are therapeutic targets for disorders associated with defective RHO function. Methods for identifying modulators of RHO, comprising screening for agents that modulate the activity of KIF23 are provided.

摘要翻译： 人类KIF23基因被鉴定为RHO途径的调节剂，因此是与缺陷型RHO功能相关的疾病的治疗靶点。提供了用于鉴定RHO调节剂的方法，包括筛选调节KIF23活性的试剂。