发明申请
US20110118278A1 CARBAMOYL DERIVATIVES OF BICYCLIC CARBONYLAMINO-PYRAZOLES AS PRODRUGS
审中-公开
作为原料的双环碳酰胺基吡唑的卡巴衍生物
- 专利标题： CARBAMOYL DERIVATIVES OF BICYCLIC CARBONYLAMINO-PYRAZOLES AS PRODRUGS
- 专利标题（中）： 作为原料的双环碳酰胺基吡唑的卡巴衍生物
-
申请号： US12991564申请日： 2009-05-14
-
公开(公告)号： US20110118278A1公开(公告)日： 2011-05-19
- 发明人: Maurizio Pulici , Paolo Polucci
- 申请人： Maurizio Pulici , Paolo Polucci
- 申请人地址： IT Nerviano (MI)
- 专利权人： NERVIANO MEDICAL SCIENCES S.R.L.
- 当前专利权人： NERVIANO MEDICAL SCIENCES S.R.L.
- 当前专利权人地址： IT Nerviano (MI)
- 优先权： EP08156262.1 20080515
- 国际申请： PCT/EP09/55802 WO 20090514
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; C07D401/14 ; C07D401/12 ; C07D495/04 ; A61K31/4162 ; A61K31/454 ; A61P35/00
摘要：
There are provided bicyclic carbonylamino-pyrazoles of formula (I), wherein the variables are as specified in the claims, for use as medicament, in particular for the treatment of diseases due to the malfunctioning of protein kinases (PKs), such as cancer, pharmaceutical compositions comprising such carbamoyl derivatives, and their use as prodrugs of therapeutically active agents. Method of treatment and some new bicyclic carbonylamino-pyrazoles are also object of the present invention.
信息查询
IPC分类:
