发明申请
- 专利标题: DELETION MUTANTS OF FLAGELLIN AND METHODS OF USE
- 专利标题(中): FLAGELLIN的去除突变体及其使用方法
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申请号: US12905584申请日: 2010-10-15
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公开(公告)号: US20110135680A1公开(公告)日: 2011-06-09
- 发明人: Langzhou Song , Lynda G. Tussey , Alan R. Shaw , Robert S. Becker , Yi Zhang , Scott W. Umlauf , David N. Taylor , Ge Liu , Mark D. Yeager
- 申请人: Langzhou Song , Lynda G. Tussey , Alan R. Shaw , Robert S. Becker , Yi Zhang , Scott W. Umlauf , David N. Taylor , Ge Liu , Mark D. Yeager
- 主分类号: A61K39/385
- IPC分类号: A61K39/385 ; C07K14/195 ; C07K19/00 ; A61K39/00 ; A61P37/04 ; B82Y5/00
摘要:
Compositions that include Toll-like Receptor 5 agonists and at least a portion of at least one viral antigen can be employed in methods that stimulate an immune response in a subject, in particular, a protective immune response in a subject. Compositions can be associated with particles and employed in the methods in relatively low doses to provide protective immunity to viral infection.
公开/授权文献
- US08932605B2 Deletion mutants of flagellin and methods of use 公开/授权日:2015-01-13
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