发明申请
- 专利标题： DEFENSIN-ANTIGEN FUSION PROTEINS
- 专利标题（中）： 防御素抗原蛋白
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申请号： US13019160申请日： 2011-02-01
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公开(公告)号： US20110135715A1公开(公告)日： 2011-06-09
- 发明人: Larry W. Kwak , Arya Biragyn
- 申请人： Larry W. Kwak , Arya Biragyn
- 专利权人： The Government of the United States of America as represented by the Secretary of the Department of,Health and Human Services
- 当前专利权人： The Government of the United States of America as represented by the Secretary of the Department of,Health and Human Services
- 主分类号： A61K9/127
- IPC分类号： A61K9/127 ; A61K39/12 ; A61K39/00 ; A61K39/21 ; A61K38/20 ; A61K38/21 ; A61K38/19 ; A61K39/395 ; C12N15/63 ; A61P37/04 ; A61P31/12 ; A61P31/18 ; A61P35/00
摘要：
The present invention relates to a vaccine for increasing the immunogenicity of a tumor antigen thus allowing treatment of cancer, as well as a vaccine that increases the immunogenicity of a viral antigen, thus allowing treatment of viral infection, including immunodeficiency virus (HIV) infection. In particular, the present invention provides a fusion protein comprising a defensin fused to either a tumor antigen or viral antigen which is administered as either a protein or nucleic acid vaccine to elicit an immune response effective in treating cancer or effective in treating or preventing viral infection.
公开/授权文献
- US08084250B2 Defensin-antigen fusion proteins 公开/授权日：2011-12-27
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