发明申请
- 专利标题: CELL CULTURE SUBSTRATE AND ITS PRODUCTION METHOD
- 专利标题(中): 细胞培养基质及其生产方法
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申请号: US13020193申请日: 2011-02-03
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公开(公告)号: US20110136234A1公开(公告)日: 2011-06-09
- 发明人: Shin OHYA , Takashi Inoue , Takatoki Yamamoto , Teruo Fujii , Yasuyuki Sakai , Masaki Nishikawa , Hitomi Sakai , Hirosuke Naruto
- 申请人: Shin OHYA , Takashi Inoue , Takatoki Yamamoto , Teruo Fujii , Yasuyuki Sakai , Masaki Nishikawa , Hitomi Sakai , Hirosuke Naruto
- 优先权: JP2006-215799 20060808
- 主分类号: C12N5/07
- IPC分类号: C12N5/07 ; C12N5/0735
摘要:
A cell culture substrate which is durable and which can be readily produced in commercial scale at a low cost, and its production method are provided. The cell culture substrate comprises a substrate and a layer formed by surface modification, which comprises a polymer containing amino group produced by reacting a polymer represented by the following formula (II): (wherein n is 0 or a positive integer, and m is a positive integer, the n and m representing degree of polymerization) formed by chemical vapor deposition of formyl[2.2]paracyclophane represented by the following formula (I): (wherein k is 0 or 1) with a polymer having at least one amino group (—NH2) capable of forming Schiff base in its monomer. The production method of the cell culture substrate comprises the step of synthesizing such polymer on the substrate.
公开/授权文献
- US08383409B2 Cell culture substrate and its production method 公开/授权日:2013-02-26