发明申请
- 专利标题： Bicyclic heterocycles, pharmaceutical compositions containing these compounds, the use thereof and processes for the preparation thereof
- 专利标题（中）： 双环杂环，含有这些化合物的药物组合物，其用途及其制备方法
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申请号： US13027669申请日： 2011-02-15
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公开(公告)号： US20110136806A1公开(公告)日： 2011-06-09
- 发明人: Frank HIMMELSBACH , Birgit JUNG
- 申请人： Frank HIMMELSBACH , Birgit JUNG
- 申请人地址： DE Ingelheim am Rhein
- 专利权人： BOEHRINGER INGELHEIM INTERNATIONAL GMBH
- 当前专利权人： BOEHRINGER INGELHEIM INTERNATIONAL GMBH
- 当前专利权人地址： DE Ingelheim am Rhein
- 优先权： EP05107679.2 20050822
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D401/12 ; C07D413/14 ; C07D239/94 ; A61K31/517 ; A61P1/00 ; A61P35/00 ; A61P11/00
摘要：
The invention relates to bicyclic heterocycles of general formula (I), in which Ra, Rb, Rc, Rd, Re and X are as defined in claim 1, the tautomers, stereoisomers, mixtures and salts thereof, in particular, the physiologically-acceptable salts thereof with inorganic and organic acids with useful pharmacological properties, in particular, an inhibitory effect on signal transduction brought about by tyrosine kinases, the use thereof for the treatment of diseases, in particular of tumour diseases and benign prostatic hyperplasia (BPH), diseases of the lungs and airways and production thereof.