发明申请
- 专利标题: WNT PROTEIN SIGNALLING INHIBITORS
- 专利标题(中): WNT蛋白信号抑制剂
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申请号: US12994661申请日: 2009-05-27
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公开(公告)号: US20110136813A1公开(公告)日: 2011-06-09
- 发明人: Lawrence Lum , Michael G. Roth , Baozhi Chen , Chuo Chen , Michael E. Dodge , Wei Tang
- 申请人: Lawrence Lum , Michael G. Roth , Baozhi Chen , Chuo Chen , Michael E. Dodge , Wei Tang
- 国际申请: PCT/US09/45340 WO 20090527
- 主分类号: A61K31/4709
- IPC分类号: A61K31/4709 ; C12N5/071 ; A61K31/403 ; A61K31/519 ; A61K31/517 ; A61K31/502 ; C07D401/12 ; C07D403/10 ; C07D209/76 ; C07D471/04 ; A61P35/00 ; A61P25/28 ; A61P3/10
摘要:
The present invention generally relates to protein signalling. In particular, compounds that inhibit the Wnt protein signalling pathway are disclosed. Such compounds may be used in the treatment of Wnt protein signalling-related diseases and conditions such as cancer, degenerative diseases, type II diabetes and osteopetrosis.
公开/授权文献
- US08445491B2 Wnt protein signalling inhibitors 公开/授权日:2013-05-21
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