发明申请
US20110150831A1 NOVEL NAPHTHYRIDINE DERIVATIVES AND THE USE THEREOF AS KINASE INHIBITORS
有权
新型萘啶衍生物及其作为激酶抑制剂的用途
- 专利标题: NOVEL NAPHTHYRIDINE DERIVATIVES AND THE USE THEREOF AS KINASE INHIBITORS
- 专利标题(中): 新型萘啶衍生物及其作为激酶抑制剂的用途
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申请号: US12953680申请日: 2010-11-24
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公开(公告)号: US20110150831A1公开(公告)日: 2011-06-23
- 发明人: Tilmann SCHUSTER , Matthias GERLACH , Irene SEIPELT , Emmanuel POLYMEROPOULOS , Gilbert MUELLER , Eckhard GUENTHER , Pascal MARCHAND , Julien DEFAUX
- 申请人: Tilmann SCHUSTER , Matthias GERLACH , Irene SEIPELT , Emmanuel POLYMEROPOULOS , Gilbert MUELLER , Eckhard GUENTHER , Pascal MARCHAND , Julien DEFAUX
- 申请人地址: DE Frankfurt am Main
- 专利权人: AETERNA ZENTARIS GmbH
- 当前专利权人: AETERNA ZENTARIS GmbH
- 当前专利权人地址: DE Frankfurt am Main
- 优先权: EP09177132.9 20091126
- 主分类号: A61K31/4375
- IPC分类号: A61K31/4375 ; C07D471/04 ; A61K31/5377 ; A61K31/444 ; A61K38/46 ; A61K38/14 ; A61K33/24 ; A61K31/675 ; A61K31/7068 ; A61K31/704 ; A61K31/7048 ; A61K38/21 ; A61K39/395 ; A61K38/12 ; A61K31/655 ; A61K31/7076 ; A61P9/10 ; A61P1/16 ; A61P17/06 ; A61P35/00
摘要:
The present invention relates to kinase modulators of the naphthyridine type and to the preparation and use thereof as medicaments for the modulation of misdirected cellular signal transduction processes, in particular for influencing the function of tyrosine and serine/threonine kinases and for the treatment of malignant or benign tumours and other disorders based on pathological cell proliferation, such as, for example, restenosis, psoriasis, arteriosclerosis and cirrhosis of the liver.
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