发明申请
US20110152318A1 NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
有权
新型化合物,异构体或其药学上可接受的盐作为VANILLOID受体拮抗剂和含有其的药物组合物
- 专利标题: NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
- 专利标题(中): 新型化合物,异构体或其药学上可接受的盐作为VANILLOID受体拮抗剂和含有其的药物组合物
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申请号: US13002289申请日: 2009-07-02
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公开(公告)号: US20110152318A1公开(公告)日: 2011-06-23
- 发明人: Byoung Young Woo , Sun-Young Kim , Yeonjoon Kim , Song Seok Shin , Jin Kwan Kim , Ki-Wha Lee , Dong Hyun Kim , Kyung Min Lim , Joo-Hyun Moh , Yeon Su Jeong , Jin Kyu Choi , Hyun Ju Koh , Jeongho Lee , Hyuk Kim , Jeong Hoon Yoon , Funan Li , Jee-Suk Kim , Young-Ger Suh
- 申请人: Byoung Young Woo , Sun-Young Kim , Yeonjoon Kim , Song Seok Shin , Jin Kwan Kim , Ki-Wha Lee , Dong Hyun Kim , Kyung Min Lim , Joo-Hyun Moh , Yeon Su Jeong , Jin Kyu Choi , Hyun Ju Koh , Jeongho Lee , Hyuk Kim , Jeong Hoon Yoon , Funan Li , Jee-Suk Kim , Young-Ger Suh
- 申请人地址: KR Yongsan-gu, Seoul
- 专利权人: Amorepacific Corporation
- 当前专利权人: Amorepacific Corporation
- 当前专利权人地址: KR Yongsan-gu, Seoul
- 国际申请: PCT/KR2009/003627 WO 20090702
- 主分类号: A61K31/421
- IPC分类号: A61K31/421 ; C07D263/48 ; C07D277/56 ; C07D413/04 ; C07D333/38 ; A61K31/426 ; A61K31/4709 ; A61K31/381 ; A61K31/4439 ; A61P29/00 ; A61P25/00 ; A61P25/28 ; A61P13/00 ; A61P1/00 ; A61P1/04 ; A61P11/14 ; A61P11/06 ; A61P17/04 ; A61P17/06 ; A61P17/00 ; A61P9/10 ; A61P17/14
摘要:
This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1) antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, heart disease and so on.
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