发明申请
- 专利标题： HUMANIZED ANTIBODIES THAT SEQUESTER AMYLOID BETA PEPTIDE
- 专利标题（中）： 氨基酸肽序列的人类抗体
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申请号： US12976282申请日： 2010-12-22
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公开(公告)号： US20110158986A1公开(公告)日： 2011-06-30
- 发明人: David M. Holtzman , Ronald DeMattos , Kelly R. Bales , Steven M. Paul , Naoya Tsurushita , Maximiliano Vasquez
- 申请人： David M. Holtzman , Ronald DeMattos , Kelly R. Bales , Steven M. Paul , Naoya Tsurushita , Maximiliano Vasquez
- 申请人地址： US IN Indianapolis US MO St. Louis
- 专利权人： ELI LILLY CORPORATION,WASHINGTON UNIVERSITY
- 当前专利权人： ELI LILLY CORPORATION,WASHINGTON UNIVERSITY
- 当前专利权人地址： US IN Indianapolis US MO St. Louis
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/18 ; C07H21/00 ; C12N15/63 ; C12N5/10 ; A61P25/00 ; A61P25/28
摘要：
A method to treat conditions characterized by formation of amyloid plaques both prophylactically and therapeutically is described. The method employs humanized antibodies which sequester soluble Aβ peptide from human biological fluids or which preferably specifically bind an epitope contained within position 13-28 of the amyloid beta peptide Aβ.
公开/授权文献
- US08591894B2 Humanized antibodies that sequester amyloid beta peptide 公开/授权日：2013-11-26
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