发明申请
US20110159034A1 METHODS AND REAGENTS FOR VACCINATION WHICH GENERATE A CD8 T CELL IMMUNE RESPONSE
审中-公开
产生CD8细胞免疫应答的疫苗的方法和试剂
- 专利标题： METHODS AND REAGENTS FOR VACCINATION WHICH GENERATE A CD8 T CELL IMMUNE RESPONSE
- 专利标题（中）： 产生CD8细胞免疫应答的疫苗的方法和试剂
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申请号： US12940627申请日： 2010-11-05
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公开(公告)号： US20110159034A1公开(公告)日： 2011-06-30
- 发明人: Andrew McMICHAEL , Adrian V.S. Hill , Sarah C. Gilbert , Jörg Schneider , Magdalena Plebanski , Tomas Hanke , Geoffrey L. Smith , Tom Blanchard
- 申请人： Andrew McMICHAEL , Adrian V.S. Hill , Sarah C. Gilbert , Jörg Schneider , Magdalena Plebanski , Tomas Hanke , Geoffrey L. Smith , Tom Blanchard
- 优先权： GB9711957.2 19970609
- 主分类号： A61K39/295
- IPC分类号： A61K39/295 ; A61K39/235 ; A61P37/04 ; A61P31/20
摘要：
New methods and reagents for vaccination are described which generate a CD8 T cell immune response against malarial and other antigens such as viral and tumour antigens. Novel vaccination regimes are described which employ a priming composition and a boosting composition, the boosting composition comprising a non-replicating or replication-impaired pox virus vector carrying at least one CD8 T cell epitope which is also present in the priming composition.
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