发明申请
- 专利标题: IMMUNOGENIC PEPTIDES AND METHODS OF USE
- 专利标题(中): 免疫原性和使用方法
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申请号: US13025094申请日: 2011-02-10
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公开(公告)号: US20110165117A1公开(公告)日: 2011-07-07
- 发明人: Jeffrey Schlom , Kwong-Yok Tsang , Ira H. Pastan
- 申请人: Jeffrey Schlom , Kwong-Yok Tsang , Ira H. Pastan
- 专利权人: The Gov't of USA as represented by the Secretary of the Department of Health and Human Services,National Institutes of Health
- 当前专利权人: The Gov't of USA as represented by the Secretary of the Department of Health and Human Services,National Institutes of Health
- 主分类号: A61K38/21
- IPC分类号: A61K38/21 ; A61K38/20 ; A61P35/00 ; A61K39/00 ; A61K35/12 ; C12N7/01 ; C12N5/10 ; C12N5/02 ; C12N15/63 ; A61K38/00 ; A61K31/7088 ; C07K14/435 ; C07H21/04
摘要:
The PAGE4 gene is expressed in reproductive tissues, and is expressed in reproductive cancers, such as prostate cancer, uterine cancer, and testicular cancer. Immunogenic PAGE4 polypeptides are disclosed herein, as are nucleic acids encoding the immunogenic PAGE4 polypeptides, vectors including these polynucleotides, and host cells transformed with these vectors. These polypeptides, polynucleotides, vectors, and host cells can be used to induce an immune response to PAGE4. Diagnostic methods to detect PAGE4 are also described.
公开/授权文献
- US09175057B2 Immunogenic peptides and methods of use 公开/授权日:2015-11-03
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