发明申请
US20110166178A1 Methods for treating anemia using inhibitors of hypoxia-inducible factor (HIF) hydroxylase
审中-公开
使用缺氧诱导因子(HIF)羟化酶抑制剂治疗贫血的方法
- 专利标题: Methods for treating anemia using inhibitors of hypoxia-inducible factor (HIF) hydroxylase
- 专利标题(中): 使用缺氧诱导因子(HIF)羟化酶抑制剂治疗贫血的方法
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申请号: US12932151申请日: 2011-02-17
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公开(公告)号: US20110166178A1公开(公告)日: 2011-07-07
- 发明人: Stephen J. Klaus , Al Y. Lin , Thoams B. Neff , Qingjian Wang , Volkmar Guenzler-Pukall , Michael P. Arend , Lee A. Flippin , Alex Melekhov
- 申请人: Stephen J. Klaus , Al Y. Lin , Thoams B. Neff , Qingjian Wang , Volkmar Guenzler-Pukall , Michael P. Arend , Lee A. Flippin , Alex Melekhov
- 申请人地址: US CA San Francisco
- 专利权人: FibroGen, Inc.
- 当前专利权人: FibroGen, Inc.
- 当前专利权人地址: US CA San Francisco
- 主分类号: A61K31/472
- IPC分类号: A61K31/472 ; A61P7/06
摘要:
The present invention relates to methods for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo. Methods for treating, pretreating or preconditioning, or preventing erythropoietin-associated conditions are also included. Compounds for use in these methods are provided, as are methods of identifying such compounds.
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