发明申请
- 专利标题： Oral recombinant helicobacter pylori vaccine and preparing method thereof
- 专利标题（中）： 口服重组幽门螺杆菌疫苗及其制备方法
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申请号： US12310658申请日： 2007-09-05
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公开(公告)号： US20110171315A1公开(公告)日： 2011-07-14
- 发明人: Quanming Zou , Wende Tong , Xuhu Mao , Gang Guo , Dongshui Lu , Chao Wu , Hao Zeng , Yichao Wang , Jun Yang , Weijun Zhang , Kaiyun Liu , Ping Luo
- 申请人： Quanming Zou , Wende Tong , Xuhu Mao , Gang Guo , Dongshui Lu , Chao Wu , Hao Zeng , Yichao Wang , Jun Yang , Weijun Zhang , Kaiyun Liu , Ping Luo
- 申请人地址： CN Chongquing City
- 专利权人： Chongqing Kang Wei Biotechnology Co. Ltd.
- 当前专利权人： Chongqing Kang Wei Biotechnology Co. Ltd.
- 当前专利权人地址： CN Chongquing City
- 优先权： CN200610095094.0 20060905
- 国际申请： PCT/CN2007/002655 WO 20070905
- 主分类号： A61K9/14
- IPC分类号： A61K9/14 ; C12N9/96 ; A61K39/116 ; C07H21/00 ; C12N15/63 ; A61P37/04 ; A61P31/04
摘要：
The invention relates to a recombinant protein used for immunoprophylaxis of human Helicobacter pylori infection and a degradable slow-releasing microsphere-encapsulated oral vaccine preparation prepared from the same, and the preparation method thereof. Said recombinant protein is composed of A2 subunit and B subunit of the LT of enterotoxigenic Escherichia coli and urease B subunit. The vaccine provided in the invention used in human Helicobacter pylori infection is safe and effective and convenient for oral intake.
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