发明申请
- 专利标题： GENETIC VARIATIONS ASSOCIATED WITH DRUG RESISTANCE
- 专利标题（中）： 与耐药性相关的遗传变异
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申请号： US12922420申请日： 2009-03-12
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公开(公告)号： US20110177099A1公开(公告)日： 2011-07-21
- 发明人: Mark Lackner , Lukas C. Amler , Guy Cavet , Carol O'Brien , Ajay Pandita
- 申请人： Mark Lackner , Lukas C. Amler , Guy Cavet , Carol O'Brien , Ajay Pandita
- 国际申请： PCT/US09/36985 WO 20090312
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C12Q1/68 ; C40B30/04 ; G01N33/574 ; A61K31/713 ; A61P35/00
摘要：
Methods and compositions are provided to determine if a cancer is resistant to treatment with anti-mitotic agents, including treatment with T-DM1. The methods relate to determining if the ABCC3 gene is amplified and/or overexpressed in the cancer.
公开/授权文献
- US09879267B2 Genetic variations associated with drug resistance 公开/授权日：2018-01-30
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