发明申请
- 专利标题: HETEROCYCLIC COMPOUND AND USE THEREOF
- 专利标题(中): 杂环化合物及其用途
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申请号: US12999428申请日: 2009-06-17
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公开(公告)号: US20110178057A1公开(公告)日: 2011-07-21
- 发明人: Takanobu Kuroita , Yasuhiro Imaeda , Kouichi Iwanaga , Naohiro Taya , Hidekazu Tokuhara , Yoshiyuki Fukase
- 申请人: Takanobu Kuroita , Yasuhiro Imaeda , Kouichi Iwanaga , Naohiro Taya , Hidekazu Tokuhara , Yoshiyuki Fukase
- 专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人: Takeda Pharmaceutical Company Limited
- 优先权: JP2008-161049 20080619; JP2009-004882 20090113
- 国际申请: PCT/JP2009/061438 WO 20090617
- 主分类号: A61K31/454
- IPC分类号: A61K31/454 ; C07D413/14 ; C07D471/04 ; C07D401/14 ; C07D401/12 ; A61K31/5377 ; A61K31/4545 ; A61P9/12 ; A61P9/00
摘要:
Compounds represented by the formulas (I) (II) wherein each symbol is as defined in the specification, and a pro-drug thereof have a superior renin inhibitory activity, and are useful as agents for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension and the like.
公开/授权文献
- US08466282B2 Heterocyclic compound and use thereof 公开/授权日:2013-06-18