发明申请
US20110178274A1 CANINE TRANSIENT RECEPTOR POTENTIAL V2 (CTRPV2) AND METHODS OF SCREENING FOR TRPV2 CHANNEL MODULATORS
审中-公开
可能的瞬态受体电位V2(CTRPV2)和TRPV2通道调制器的筛选方法
- 专利标题: CANINE TRANSIENT RECEPTOR POTENTIAL V2 (CTRPV2) AND METHODS OF SCREENING FOR TRPV2 CHANNEL MODULATORS
- 专利标题(中): 可能的瞬态受体电位V2(CTRPV2)和TRPV2通道调制器的筛选方法
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申请号: US13037125申请日: 2011-02-28
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公开(公告)号: US20110178274A1公开(公告)日: 2011-07-21
- 发明人: Ning QIN , Christopher M. Flores , Michael P. Neeper
- 申请人: Ning QIN , Christopher M. Flores , Michael P. Neeper
- 申请人地址: BE Beerse
- 专利权人: Janssen Pharmaceutica, N.V.
- 当前专利权人: Janssen Pharmaceutica, N.V.
- 当前专利权人地址: BE Beerse
- 主分类号: C07K14/435
- IPC分类号: C07K14/435
摘要:
A recombinant canine TRPV2 channel which has been prepared by cDNA cloning and polymerase chain reaction techniques is disclosed. Expression systems for these channels and an assay using the expression systems are also disclosed. The recombinant TRPV2 channel can be used in assays to evaluate compounds which directly or indirectly interact with or bind to TRPV2 channel.
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