发明申请
US20110178326A1 UNSATURATED CINACALCET SALTS AND PROCESSES FOR PREPARING CINACALCET HYDROCHLORIDE
审中-公开
不饱和的CINACALCET SALTS和制备CINACALCET HYDROCHLORIDE的方法
- 专利标题: UNSATURATED CINACALCET SALTS AND PROCESSES FOR PREPARING CINACALCET HYDROCHLORIDE
- 专利标题(中): 不饱和的CINACALCET SALTS和制备CINACALCET HYDROCHLORIDE的方法
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申请号: US13057796申请日: 2009-08-06
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公开(公告)号: US20110178326A1公开(公告)日: 2011-07-21
- 发明人: Sonny Sebastian , Seetha Rama Sarma , Katikireddy Ramamurthy , Nitin Sharadchandra Pradhan
- 申请人: Sonny Sebastian , Seetha Rama Sarma , Katikireddy Ramamurthy , Nitin Sharadchandra Pradhan
- 申请人地址: IS Hafnarfjordur
- 专利权人: ACTAVIS GROUP PTC EHF
- 当前专利权人: ACTAVIS GROUP PTC EHF
- 当前专利权人地址: IS Hafnarfjordur
- 优先权: IN1887/CHE/2008 20080806
- 国际申请: PCT/IB09/06708 WO 20090806
- 主分类号: C07C271/14
- IPC分类号: C07C271/14 ; C07C209/70 ; C07C209/68 ; C07C211/30 ; C07C209/86
摘要:
Disclosed herein are convenient, industrially advantageous and environmentally friendly processes for the preparation of cinacalcet hydrochloride. Disclosed also herein are novel hydrochloride, oxalate and di-p-toluoyl-L-(+)-tartrate salts of (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propylene]-1-naphthalenemethaneamine (unsaturated cinacalcet), solid state forms of the salts, and a process for their preparation thereof.
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