发明申请
US20110183358A1 METHODS AND COMPOSITIONS FOR DEREPRESSION OF IAP-INHIBITED CASPASE
审中-公开
用于抑制IAP抑制CASPASE的方法和组合物
- 专利标题: METHODS AND COMPOSITIONS FOR DEREPRESSION OF IAP-INHIBITED CASPASE
- 专利标题(中): 用于抑制IAP抑制CASPASE的方法和组合物
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申请号: US11886385申请日: 2006-03-17
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公开(公告)号: US20110183358A1公开(公告)日: 2011-07-28
- 发明人: John C. Reed , Richard A. Houghten , Adel Nefzi , John M. Ostresh , Kate Welsh , Clemencia Pinilla
- 申请人: John C. Reed , Richard A. Houghten , Adel Nefzi , John M. Ostresh , Kate Welsh , Clemencia Pinilla
- 申请人地址: US CA La Jolla US CA San Diego
- 专利权人: THE BURNHAM INSTITUTE,TORREY PINES INSTITUTE FOR MOLECULAR STUDIES
- 当前专利权人: THE BURNHAM INSTITUTE,TORREY PINES INSTITUTE FOR MOLECULAR STUDIES
- 当前专利权人地址: US CA La Jolla US CA San Diego
- 国际申请: PCT/US2006/009695 WO 20060317
- 主分类号: G01N33/53
- IPC分类号: G01N33/53
摘要:
The invention provides isolated agents having novel chemical structures and possessing superior activity as derepressors of IAP inhibited caspase. The invention further provides a method of derepressing an IAP-inhibited caspase. The invention further provides assay methods employing labeled compounds of the invention, especially fluorescent labeled compounds.
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