发明申请
- 专利标题: 5HT7 RECEPTOR LIGANDS AND COMPOSITIONS COMPRISING THE SAME
- 专利标题(中): 5HT7受体配体及其组合物
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申请号: US13063947申请日: 2009-07-31
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公开(公告)号: US20110183991A1公开(公告)日: 2011-07-28
- 发明人: Rosalia Pascual-Ramon , Helmut H. Buschmann
- 申请人: Rosalia Pascual-Ramon , Helmut H. Buschmann
- 申请人地址: ES Barcelona
- 专利权人: LABORATORIOS DEL DR. ESTEVE, S.A.
- 当前专利权人: LABORATORIOS DEL DR. ESTEVE, S.A.
- 当前专利权人地址: ES Barcelona
- 优先权: EP08380239.7 20080801
- 国际申请: PCT/EP09/59918 WO 20090731
- 主分类号: A61K31/496
- IPC分类号: A61K31/496 ; C07D403/06 ; A61P13/00 ; C07D401/06 ; A61P1/00 ; A61P9/12 ; A61P25/28 ; A61P25/18 ; A61P25/00 ; A61P25/24 ; A61P25/06 ; A61P25/22
摘要:
The present invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, especially as agonists, identified by using a pharmacophore and a descriptor's profile filter as well as to pharmaceutical compositions comprising them. These compounds are useful in therapy in particular for the treatment and or prophylaxis of a disease in which 5-HT7 is involved, such as CNS disorders.
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