发明申请
- 专利标题: NOVEL COMPOUNDS THAT ARE ERK INHIBITORS
- 专利标题(中): 新的化合物是ERK抑制剂
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申请号: US12918099申请日: 2009-02-19
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公开(公告)号: US20110189192A1公开(公告)日: 2011-08-04
- 发明人: Alan B. Cooper , Yang Nan , Yongqi Deng , Gerald W. Shipps, JR. , Neng-Yang Shih , Hugh Y. Zhu , Joseph M. Kelly , Subrahmanyam Gudipati , Ronald J. Doll , Mehul F. Patel , Jagdish A. Desai , James J-S Wang , Sunil Paliwal , Hon-Chung Tsui , Sobhana Babu Boga , Abdul-Basit Alhassan , Xiaolei Gao , Liang Zhu , Xin Yao
- 申请人: Alan B. Cooper , Yang Nan , Yongqi Deng , Gerald W. Shipps, JR. , Neng-Yang Shih , Hugh Y. Zhu , Joseph M. Kelly , Subrahmanyam Gudipati , Ronald J. Doll , Mehul F. Patel , Jagdish A. Desai , James J-S Wang , Sunil Paliwal , Hon-Chung Tsui , Sobhana Babu Boga , Abdul-Basit Alhassan , Xiaolei Gao , Liang Zhu , Xin Yao
- 国际申请: PCT/US09/34447 WO 20090219
- 主分类号: A61K31/444
- IPC分类号: A61K31/444 ; C07D401/14 ; C07D409/14 ; C07D417/14 ; A61K31/501 ; A61K39/395 ; A61K31/7052 ; A61P35/02 ; A61P35/00
摘要:
Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts, and solvates thereof. Q is a tetrahydropyridinyl ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
公开/授权文献
- US08716483B2 Compounds that are ERK inhibitors 公开/授权日:2014-05-06
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