发明申请
US20110189231A1 Compositions Comprising Salmonella Porins and Uses Thereof as Adjuvants and Vaccines
审中-公开
组成包括沙门氏菌和其用途作为佐剂和疫苗
- 专利标题： Compositions Comprising Salmonella Porins and Uses Thereof as Adjuvants and Vaccines
- 专利标题（中）： 组成包括沙门氏菌和其用途作为佐剂和疫苗
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申请号： US12999989申请日： 2009-06-17
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公开(公告)号： US20110189231A1公开(公告)日： 2011-08-04
- 发明人: Denis Leclerc , Constantino Roberto Lopez-Macias, III
- 申请人： Denis Leclerc , Constantino Roberto Lopez-Macias, III
- 国际申请： PCT/CA2009/000816 WO 20090617
- 主分类号： A61K39/145
- IPC分类号： A61K39/145 ; A61K39/39 ; A61P37/04 ; A61P31/16
摘要：
Adjuvants comprising OmpC porin, OmpF porin, or a combination thereof, are provided. The adjuvants can be administered to a subject in combination with antigenic material in order to potentiate the immunogenic effect of the antigenic material. Also provided are products comprising antigenic material in combination with OmpC and/or OmpF, including products comprising a pre-formulated vaccine in combination with OmpC and/or OmpF. Further provided is the use of OmpC and/or OmpF to improve the effect of a pre-formulated vaccine.
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