发明申请
- 专利标题： Antagonists of Prostaglandin D2 Receptors
- 专利标题（中）： 前列腺素D2受体拮抗剂
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申请号： US12999621申请日： 2009-07-02
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公开(公告)号： US20110190227A1公开(公告)日： 2011-08-04
- 发明人: John Howard Hutchinson , Thomas Jon Seiders , Bowei Wang , Jeannie M. Arruda , Brian Andrew Stearns , Jeffrey Roger Roppe
- 申请人： John Howard Hutchinson , Thomas Jon Seiders , Bowei Wang , Jeannie M. Arruda , Brian Andrew Stearns , Jeffrey Roger Roppe
- 申请人地址： US CA San Diego
- 专利权人： Amira Pharmaceuticals, Inc.
- 当前专利权人： Amira Pharmaceuticals, Inc.
- 当前专利权人地址： US CA San Diego
- 国际申请： PCT/US2009/049631 WO 20090702
- 主分类号： A61K31/7028
- IPC分类号： A61K31/7028 ; C07C59/68 ; C07C317/46 ; C07D277/36 ; C07D215/36 ; C07D213/70 ; C07D213/71 ; C07D285/125 ; C07H15/203 ; A61K31/192 ; A61K31/426 ; A61K31/47 ; A61K31/435 ; A61K31/433 ; A61P11/00 ; A61P29/00 ; A61P37/08 ; A61P11/06 ; A61P9/12 ; A61P19/02 ; A61P17/06 ; A61P35/00 ; A61P43/00 ; A61P9/00 ; A61P9/10 ; A61P11/02
摘要：
Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the compounds described herein that are antagonists Of PGD2 receptors. Also described herein are methods of using such antagonists of PGD2 receptors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
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