The subject matter described herein includes methods, systems, and computer readable media for dynamic subscriber profile adaptation. According to one aspect of the subject matter described herein, a method for subscriber profile adaptation is provided. The method includes receiving, from a database that stores subscriber profile information, a message generated by the database node in response to a message received by the database node. The message generated by the database node may include subscriber profile information. The method further includes determining whether to modify the subscriber profile information based on predetermined criteria. The method further includes, in response to determining to modify the subscriber profile information, modifying the subscriber profile information and forwarding the modified information to an originator of the message generated by the database node.