发明申请
- 专利标题： Method of inhibiting prostate cancer cell proliferation
- 专利标题（中）： 抑制前列腺癌细胞增殖的方法
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申请号： US12929745申请日： 2011-02-14
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公开(公告)号： US20110195915A1公开(公告)日： 2011-08-11
- 发明人: Garry George Graham , Qihan Dong
- 申请人： Garry George Graham , Qihan Dong
- 申请人地址： AU New South Wales
- 专利权人： Scott, Kieran, Francis
- 当前专利权人： Scott, Kieran, Francis
- 当前专利权人地址： AU New South Wales
- 优先权： AUPS2826 20020607
- 主分类号： A61K38/12
- IPC分类号： A61K38/12 ; C12N5/09 ; C12Q1/68 ; A61P35/00 ; C12Q1/44
摘要：
The present invention relates to a method of inhibiting or reducing the proliferation of prostate cancer cells, such as androgen independent prostate cancer (AIPC) cells, the method comprising administering to the cells a PLA2 inhibitor. In one embodiment the PLA2 inhibitor is a conformationally constrained molecule derived from a peptide consisting essentially of amino acid residues 70-74 of a human sPLA2-IIA protein, or the equivalent residues in other sPLA2 proteins.
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