发明申请
- 专利标题： FUSED-RING DERIVATIVE AND MEDICAL APPLICATION OF SAME
- 专利标题（中）： 熔融衍生物和医学应用
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申请号： US13124345申请日： 2009-10-14
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公开(公告)号： US20110207935A1公开(公告)日： 2011-08-25
- 发明人: Kazuo Shimizu , Masato Iizuka , Hideki Fujikura , Yasushi Takigawa , Masahiro Hiratochi
- 申请人： Kazuo Shimizu , Masato Iizuka , Hideki Fujikura , Yasushi Takigawa , Masahiro Hiratochi
- 申请人地址： JP Matsumoto-shi, Nagano
- 专利权人： KISSEI PHARMACEUTICAL CO., LTD.
- 当前专利权人： KISSEI PHARMACEUTICAL CO., LTD.
- 当前专利权人地址： JP Matsumoto-shi, Nagano
- 优先权： JP2008-266088 20081015
- 国际申请： PCT/JP2009/067752 WO 20091014
- 主分类号： C07D215/52
- IPC分类号： C07D215/52 ; C07D277/56 ; C07D263/34 ; C07D275/03 ; C07D285/08 ; C07D271/06 ; C07C255/57 ; C07D231/14 ; C07D213/79
摘要：
The present invention provides compounds useful as agents for the prevention or treatment of a disease associated with abnormal plasma uric acid level and the like. The present invention relates to fused ring derivatives represented by the following formula (I) having xanthine oxidase inhibitory activities and useful as agents for the prevention or treatment of a disease associated with abnormality of plasma uric acid level, prodrugs thereof, salts thereof or the like. In the formula (I), X1 and X2 represent CH or N; ring U represents aryl or heteroaryl; m represents integral number from 0 to 2; n represents integral number from 0 to 3; R1 represents a hydroxy group, amino or C1-6 alkyl; R2 represents C1-6 alkyl, C1-6 alkoxy C1-6 alkyl or the like.
公开/授权文献
- US08263622B2 Fused-ring derivative and medical application of same 公开/授权日：2012-09-11
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