发明申请
- 专利标题: METHODS OF MODULATING IL-22 AND IL-17
- 专利标题(中): 调节IL-22和IL-17的方法
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申请号: US13048105申请日: 2011-03-15
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公开(公告)号: US20110212099A1公开(公告)日: 2011-09-01
- 发明人: Spencer C. LIANG , Lynette A. Fouser , Margot O'Toole
- 申请人: Spencer C. LIANG , Lynette A. Fouser , Margot O'Toole
- 申请人地址: US NJ Madison
- 专利权人: Wyeth LLC
- 当前专利权人: Wyeth LLC
- 当前专利权人地址: US NJ Madison
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; G01N33/68 ; C12N5/071 ; A61K38/02 ; A61P29/00 ; A61P19/02 ; A61P17/06 ; A61P37/06 ; A61P25/28 ; A61P1/18 ; A61P1/00
摘要:
The present application provides methods of modulating immune responses by using IL-22 in combination with at least one of IL-17A, IL-17F, or IL-23 or by using an IL-22 antagonist, such as an antibody or a soluble receptor or a binding protein, in combination with an antagonist of at least one of IL-17A, IL-17F, or IL-23
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