发明申请
US20110212856A1 HUMAN T2R RECEPTORS RECOGNIZING A CLASS OF BITTER MOLECULES FROM COFFEE
有权
人类T2R受体识别来自咖啡的一类双歧杆菌分子
- 专利标题： HUMAN T2R RECEPTORS RECOGNIZING A CLASS OF BITTER MOLECULES FROM COFFEE
- 专利标题（中）： 人类T2R受体识别来自咖啡的一类双歧杆菌分子
-
申请号： US13094974申请日： 2011-04-27
-
公开(公告)号： US20110212856A1公开(公告)日： 2011-09-01
- 发明人: Xiaodong Li , Hong Xu , Qing Li , Huixian Tang
- 申请人： Xiaodong Li , Hong Xu , Qing Li , Huixian Tang
- 申请人地址： US CA San Diego
- 专利权人： Senomyx, Inc.
- 当前专利权人： Senomyx, Inc.
- 当前专利权人地址： US CA San Diego
- 主分类号： C40B30/04
- IPC分类号： C40B30/04 ; G01N33/68
摘要：
The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds, i.e., chlorogenic lactone compounds that contribute at least partially to the bitter taste of many coffee beverages. The present invention further relates to the use of these receptors in assays for identifying ligands that modulate the activation of these taste receptors by chlorogenic lactones and related compounds and which may be used as additives and/or removed from foods, beverages and medicinals in order to modify (block) T2R-associated bitter taste. A preferred embodiment is the use of the identified compounds as additives in coffee and coffee-flavored foods, beverages and medicinals.
公开/授权文献
信息查询
