发明申请
US20110224263A1 Cyclic pyridyl-N-[1,3,4]-thiadiazol-2-yl-benzene sulfonamides, processes for their preparation and their use as pharmaceuticals
有权
环状吡啶基-N- [1,3,4] - 噻二唑-2-基 - 苯磺酰胺，其制备方法及其作为药物的用途
![Cyclic pyridyl-N-[1,3,4]-thiadiazol-2-yl-benzene sulfonamides, processes for their preparation and their use as pharmaceuticals](/docs/US/2011-09-15/US20110224263A1/abs.jpg.600x600.jpg)
- 专利标题： Cyclic pyridyl-N-[1,3,4]-thiadiazol-2-yl-benzene sulfonamides, processes for their preparation and their use as pharmaceuticals
- 专利标题（中）： 环状吡啶基-N- [1,3,4] - 噻二唑-2-基 - 苯磺酰胺，其制备方法及其作为药物的用途
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申请号： US12796886申请日： 2010-06-09
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公开(公告)号： US20110224263A1公开(公告)日： 2011-09-15
- 发明人: Karl SCHOENAFINGER , Stefanie KEIL , Matthias URMANN , Hans MATTER , Maike GLIEN , Wolfgang WENDLER , Ulrike Wendler
- 申请人： Karl SCHOENAFINGER , Stefanie KEIL , Matthias URMANN , Hans MATTER , Maike GLIEN , Wolfgang WENDLER , Ulrike Wendler
- 申请人地址： FR Paris
- 专利权人： SANOFI-AVENTIS
- 当前专利权人： SANOFI-AVENTIS
- 当前专利权人地址： FR Paris
- 优先权： EP07291626.5 20071226
- 主分类号： A61K31/4439
- IPC分类号： A61K31/4439 ; C07D417/12 ; A61P3/10 ; A61P3/06 ; A61P25/28
![Cyclic pyridyl-N-[1,3,4]-thiadiazol-2-yl-benzene sulfonamides, processes for their preparation and their use as pharmaceuticals](/abs-image/US/2011/09/15/US20110224263A1/abs.jpg.150x150.jpg)
摘要：
The invention relates to cyclic N-[1,3,4]-thiadiazol-2-yl-benzene sulfonamides and to their physiologically acceptable salts and physiologically functional derivatives showing PPARdelta or PPARdelta and PPARgamma agonist activity.What is described are compounds of the formula I, in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparations. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved and demyelinating and other neurodegenerative disorders of the central and peripheral nervous system.
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