发明申请
- 专利标题： MONOSPECIFIC AND MULTISPECIFIC ANTIBODIES AND METHOD OF USE
- 专利标题（中）： 单一和多重抗体及其使用方法
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申请号： US12671942申请日： 2008-08-16
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公开(公告)号： US20110229476A1公开(公告)日： 2011-09-22
- 发明人: Bing Liu , David Light , Zhuozhi Wang , Douglas Schneider
- 申请人： Bing Liu , David Light , Zhuozhi Wang , Douglas Schneider
- 申请人地址： DE Berlin
- 专利权人： BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
- 当前专利权人： BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
- 当前专利权人地址： DE Berlin
- 国际申请： PCT/EP08/06750 WO 20080816
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/44 ; G01N33/53 ; C12N9/96 ; A61P35/00 ; A61P35/02 ; A61P29/00 ; A61P3/10 ; A61P25/00 ; A61P19/02 ; A61P7/06 ; A61P17/06 ; A61P1/12 ; A61P33/06 ; A61P31/04 ; A61P31/00 ; A61P31/18 ; A61P31/06 ; A61P31/14 ; A61P31/20
摘要：
This invention relates to monospecific and multispecific antibodies that may be utilized for the diagnosis and treatment of various diseases. In addition, these antibodies may be modified by protease cleavage. Protease control or regulation may be provided by a protease site located in, for example, a linker. These protease-regulated antibodies may also be utilized for the diagnosis and treatment of various diseases.
公开/授权文献
- US09624309B2 Monospecific and multispecific antibodies and method of use 公开/授权日：2017-04-18
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