发明申请
- 专利标题： Aryl Bidentate Isonitriles and Their Uses
- 专利标题（中）： 芳基二异丁腈及其用途
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申请号： US12297513申请日： 2007-04-17
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公开(公告)号： US20110236308A1公开(公告)日： 2011-09-29
- 发明人: David R. Elmaleh , Timothy M. Shoup , Alan J. Fischman , Bhaskar C. Das
- 申请人： David R. Elmaleh , Timothy M. Shoup , Alan J. Fischman , Bhaskar C. Das
- 申请人地址： US MA Boston
- 专利权人： The General Hospital Corporation
- 当前专利权人： The General Hospital Corporation
- 当前专利权人地址： US MA Boston
- 国际申请： PCT/US07/09450 WO 20070417
- 主分类号： A61K51/04
- IPC分类号： A61K51/04 ; C07C255/33 ; C07C255/51 ; C07F13/00 ; A61K47/48 ; A61P43/00
摘要：
The present invention relates generally to chelation compounds, radionuclide metal chelate compounds, i.e., complexes, and radiolabeled targeting moieties, i.e., conjugates, formed therefrom, and methods of using these compounds, complexes and conjugates for diagnostic and therapeutic purposes. This invention is more particularly related to aryl bidentate isonitrile metal complexes generated by a chemical interaction of a metal salt oxide or weak complex of the metal with aryl isonitrile bidentate ligands.
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