发明申请
- 专利标题： METHODS FOR DETERMINING A PATIENT'S SUSCEPTIBILITY OF CONTRACTING A NOSOCOMIAL INFECTION AND FOR ESTABLISHING A PROGNOSIS OF THE PROGRESSION OF SEPTIC SYNDROME
- 专利标题（中）： 确定患者承受感染性感染的可能性和建立SEPIC综合征进展预后的方法
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申请号： US13140678申请日： 2010-01-18
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公开(公告)号： US20110250592A1公开(公告)日： 2011-10-13
- 发明人: Marie-Angelique Cazalis , Alain Lepape , Guillaume Monneret , Bruno Mougin , Alexandre Pachot
- 申请人： Marie-Angelique Cazalis , Alain Lepape , Guillaume Monneret , Bruno Mougin , Alexandre Pachot
- 申请人地址： FR Lyon FR Marcy l'Etoile
- 专利权人： HOSPICES CIVILS DE LYON (HCL),BIOMERIEUX
- 当前专利权人： HOSPICES CIVILS DE LYON (HCL),BIOMERIEUX
- 当前专利权人地址： FR Lyon FR Marcy l'Etoile
- 优先权： FR0950305 20090119; FR0950306 20090119
- 国际申请： PCT/FR2010/050070 WO 20100118
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; G01N33/566 ; G01N33/53
摘要：
A method for determining a patient's susceptibility of contracting a nosocomial infection that includes obtaining a biological sample from the patient and extracting biological material from the biological sample; preparing a specific reagent of an expression product of at least one target gene selected from S100A9 and S100A8 target genes; and determining the expression of at least one of the target genes S100A9 and S100A8, where overexpression relative to a specified threshold value indicates susceptibility of contracting a nosocomial infection.
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